Chitosan-Carrageenan Polyelectrolyte Complex for the Delivery of Protein Drugs

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Freeze-dried k-carrageenan/chitosan polyelectrolyte complex-based insert: a novel intranasal delivery system for sumatriptan succinate

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Freeze-dried k-carrageenan/chitosan polyelectrolyte complex-based insert: a novel intranasal delivery system for sumatriptan succinate

Intranasal route, ensuring suitable bioavailability of medicines under circumvention of the gastrointestinal degradation and hepatic first-pass elimination, has been a popular choice for drug delivery. Among nasal dosage forms, mucoadhesive solid inserts have been shown to resist mucociliary clearance and provide a prolonged nasal residence time. Hence, the purpose of this study was the prepara...

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ژورنال

عنوان ژورنال: ISRN Biomaterials

سال: 2013

ISSN: 2314-4025

DOI: 10.5402/2013/629807